1 edition of A routine water monitoring test for mutagenic compounds found in the catalog.
|Statement||by James B. Johnston and James N. Herron|
|Series||WRC research report -- no. 141, WRC research report -- no. 141.|
|Contributions||Herron, James N., University of Illinois at Urbana-Champaign. Water Resources Center, Illinois. Environmental Protection Agency|
|LC Classifications||QD142 .J75|
|The Physical Object|
|Pagination||xii, 87 pages :|
|Number of Pages||87|
Mutagenic Effects of Environmental Contaminants investigates the mutagenic consequences of environmental contaminants, such as pesticides, industrials, food additives, drugs, and biologicals, as well as the possible relationships between mutagenesis and carcinogenesis. It describes the monitoring of chemical mutagens in the environment and the ways that genetic mutations cause Book Edition: 1. This test, also known as Salmonella/microsome, consists, basically, in the employment of strains of the auxotrophic bacteria Salmonella typhimurium, i.e., deficient in the synthesis of the aminoacid histidine; the strains of these cells are unable to grow in minimum medium, where the mutagenic compounds are able to restore the synthesis Cited by:
Test systems Although about 25 different test-systems have been described in 10 plant species, the following have been established as practical and useful for testing chemicals for mutagenic activity: (a) mitotic chromosomal damage; (b) aberrations in meiotic chromosomes; and (c) gene mutations at specific or miltiple loci. “Some of the compounds that we’ve discovered are far more mutagenic than we previously understood and may exist in the environment as a result of heavy air pollution from vehicles or some types of food preparation,” said Staci Simonich, Ph.D., professor of chemistry and toxicology in the OSU College of Agricultural Sciences and Superfund.
this test was developed to determine the mutagenic potential of a substance ames test specific terms such as free, low and reduced used on a food label are subject to ___. The Ames test and Salmonella tester strains (TA98 and TA) were used to screen for mutagenic organics in concentrates of reclaimed water (before it was spread), storm water, imported water, and unchlorinated and chlorinated ground water. While 13 of the 56 sample concentrates tested were free of mutagens, at least one mutagenic concentrate.
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Open Library is an open, editable library catalog, building towards a web page for every book ever published. Author of The place-names of England and Wales, The place-names of Scotland, The Scottish macs, A routine water monitoring test for mutagenic compounds, The Scottish Macs, Genetic engineering and new pollution control technologies.
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be A routine water monitoring test for mutagenic compounds book, although not always necessarily mutagens have characteristic mutational signatures with some.
Book/Book Chapter Title. Mutagenic activity of chemicals identified in drinking water Author(s) Simmon, VF; Kauhanen, K; Tardiff, RG has other version or edition Mutagenic activity of chemicals identified in drinking water. Editor(s) Scott, D; Bridges, B; Sobel, F Series. Should these contaminants move from the CCL to a regulatory framework, water supply utilities will incur added monitoring and testing of their water supply sources, and potentially added.
The mutagenicities of selenate (SeO 4 2−) and selenite (SeO 3 2−) were determined by two bacterial assay systems: Kada's rec-assay and Ames's Salmonella both assays, these compounds were found to be weak mutagens. In the Salmonella test, selenate ( revertants/nmole) and selenite ( revertants/nmole) gave rise to base-pair by: In water sources where bromide is present, much of the unexplained drinking water mutagencity could be due to BMX compounds (brominated analogues of MX), which are potent bacterial mutagens.
BMX compounds have proved more difficult to measure than MX and a routine method does not yet exist. In the routine São Paulo state (Brazil) surface water quality-monitoring program, which includes the Salmonella microsome mutagenicity assay as one of its parameters, a river where water is taken.
— The results of the Ames test indicates that mutagenic activity is higher with TA98 than TA; this fact indicates that the compounds responsible for the observed mutagenic effects are frameshift mutation agents in the Salmonella typhimurium bacteria; in addition, the S9 mix used increased the mutagenic response of the water samples.
Vaporization technique to measure mutagenic activity of volatiles organic chemicals in the Ames/Salmonella assay. Hughes TJ, Simmons DM, Monteith LG, Claxton LD. The purpose of this research was to develop and characterize a sensitive test method to detect mutagenic activity of volatile liquid organic chemicals (i.e, volatiles) in the Ames Cited by: Organic concentrates of water of the rivers Rhine and Meuse and a control lake were tested for mulagenic activity with the Ames Salmonella/microsome assay at 3-mth intervals for more than 1 river samples were concentrated by adsorption on XAD (10 3-fold) followed by elution with DMSO.
Using strain TA 98, all Rhine water samples except one were found to contain both direct and indirect Cited by: Abstract. A positive result in the Ames test is generally taken as a strong indication for a genotoxic (i.e.
DNA damaging) property of the test compound, often sufficient to cause termination of its development as a new therapeutic agent A number of serotonin receptor ligands have been tested for their mutagenic potential in the Ames assay at an early stage of development For several compounds Cited by: Final Report: Genotoxicity and Occurrence Assessment of Disinfection By-Product Mixtures in Drinking Water Quantitative rapid mutagenicity assays incorporating cytotoxicity measurements of DBPs enhanced the sensitivity of routine "Ames" test methods.
Mutagenic potency values can be Drinking Water, occurrence monitoring, Safe Drinking. Mutagenic activity associated with by-products of drinking water disinfection by chlorine, chlorine dioxide, ozone and UV-irradiation.
Zoeteman BC, Hrubec J, de Greef E, Kool HJ. A retrospective epidemiological study in The Netherlands showed a statistical association between chlorination by-products in drinking water and cancer of the Cited by: Among other substances, sulphur dioxide (SO2), nitric oxide (NO) and nitrogen dioxide (NO2) are parameters which are routinely measured to describe basic air quality.
Organic extracts of airborne particulate matter contain mutagenic chemical compounds of different origins. The aim of the study was to find correlations between routine monitoring data and mutagenic activity of organic Cited by: The primary purpose for disinfection of drinking water is to destroy and eliminate pathogenic organisms responsible for waterborne diseases.
Commonly used disinfectants are chlorine, chlorine Characterization of Mutagenic Compounds Formed During Disinfection of Drinking Water | SpringerLinkCited by: 1. The Mutagenic Activity of High-Energy Explosives; Contaminants of Concern at Military Training Sites Jennifer McAllister, (Hons) Thesis submitted to the Faculty of Graduate and Postdoctoral Studies, in partial fulfillment of the requirements for the degree of Master of Science, Biology.
They found that 22% of the total compounds were mutagenic, and 20% of the subset of 46 high-production compounds were mutagenic. In the absence of required testing and reporting (Guth et al. ; Schwarzman and Wilson ), these data are the best estimates available regarding the proportions of mutagens among organic compounds in current.
Test the mutagenic effects of chemicals The Ames test detects whether a given chemical can cause a reversion mutation in his- bacteria. In the Ames test, the appearance of his+ revertants in the presence of a non-mutagenic control compound indicates that.
Mutagenic effect of water samples from Riacho das Cachoeira dam using Trad-MCN test is represented in Figure 2. Influence of natural radon and metal contamination on surface water quality from a Brazilian Semiarid Region/Influencia da contaminacao natural pelo radonio e metais na qualidade das aguas superficiais da Regiao Semiarida Brasileira.
Water is an oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms. It has a role as an amphiprotic solvent, a member of greenhouse gas, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite.
It is an oxygen hydride, a mononuclear parent hydride and. Health & Environmental Research Online (HERO) Contact Us; Print HERO ID. Reference Type. Journal Article Subtype. Abstract Title. Mutagenic activity of chemicals identified in drinking water has other version or edition Mutagenic activity of chemicals identified in drinking water.
Abstract. Abstract # Reverse Mutation (Ames) test is one of the most prevalent methods that the majority of the researches use it. In this study, the mutagenic effects of the mentioned chemicals have been performed through Ames test by TA98 and TA strains (Kayraldiz et al., ; Qureshi et al., ).
Materials and Methods - Chemical Compounds.This book explains how ozone can be used to provide primary disinfection, while minimizing halogenated by-products. This is of use to those who design pilot plant studies in full scale ozone plants-and those who employ ozone and regulatory personnel.
Detailed section on components of an ozonization.